AIDS symptoms

From asymptomatic stadium of primary infection it develops to stadium of asymptomatic seroconvension, when antibodies on gp41 can be located, but there are no signs, which can show that person is HIV infected. This stadium can last a few years and is the most dangerous period for further virus transmission and infecting the others.

Clinical symptoms occur after a few years (7-10, and longer) after infection, but in same cases, when person is infected with other sexual transmitted infections symptoms can appear after a few months of infection and usually is manifested at lymph glands. Enlarged lymph glands are evident on neck and especially on backside of neck and under armpit. This stadium can last for few months when constitutional AIDS symptoms are starting to appear.

Those are characterized by loosing weight (more than 10% of normal), increased body temperature to more than 30 ° that last more than a month, permanent diarrhea or with pause of a month, fungus infections of mouth and throat, herpes on lips or genitals , which last long and can reappear. This is followed with reduction of number of erythrocytes, trombocytes, leucocytes, increased protein concentration, especially immunoglobulin in blood, and reduction of CD4 T lymphocytes in blood. Now changes on periphery and central nerve system (AIDS Dementia Complex) are occurring and those are leading to severe disorders with loosing orientation in time and place and unrecognizing surrounding.

Different types of opportunistic theory are developed, with microorganisms that by default do not cause disease among young healthy people or clinical picture of other infections that is less sensitive on usual therapy. There are infections with protozoompneumacystis carinii, kriptokokoza, criptosporiodoza, toxoplazmoza which cause the highest percent of deadly results among HIV infected persons, then diseases caused by matter of tuberculoses (mycobaterium tuberkuloze) as well as with untypical mycobacterium, infections Candidiasis, Aspergilosis and the other viruses from herpes group as Citomegalo virus (CMV) and Ebstein Bar virus (EBV), and other pathogens and microorganism pathogens.

In this stadium tumors appear, before all Caposhi sarcoma that can spread to skin and internal organs, and cancers of B lymphocytes, so called B lymphomas that are usually developed on cerebrum and are cause for death at HIV infected persons.

As possibility of immunology defense is linked with basic regulatory cell of immune system CD 4 T lymphocyte, destroying these cells is diminishing defense possibilities. Specifying the number of CD 4 T lymphocytes in blood can anticipate transit from asymptomatic infection phase to developed infection phase and cancer (AIDS stadium).

It is considered that when number of CD4T lymphocytes in periphery blood of healthy person, falls from 1000 on cubic millimeter to under 200, and HIV infection develops in AIDS stadium, where all basic infection forms and tumors emerge.

HIV doesn't kill infected, but reduces their immunology defense, destroying CD4T lymphocytes, and by that is preventing large number of pathogens and pathogens microorganisms to lead to hard infections and cancers, which are difficult to cure and result with death of infected person.

Apart from mentioned symptoms, developed disease is marked by following symptoms and signs:
  • Symptoms of specific opportunistic infections (candidaze, pneumocystoze);
  • Cancer (Kapošijev sarcoma);
  • Rash;
  • Headache .

Progress of characteristic infections and tumors can be first sign of AIDS in some cases.

In addition, following symptoms can be linked with AIDS:

  • disorders in speaking;
  • loosing musculature weight;
  • reduced intellectual functions;
  • elbows swelling;
  • pain at elbows;
  • elbows inflexibility;
  • intolerance to cold;
  • pain in bones;
  • pain in chest, back and abdomen;
  • skin itching;
  • sensitivity on light and etc.